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预出版
2018/11/9 0:18:58 | Browse: 284 | 下载: 237
| Publication Name |
世界华人消化杂志 |
| 手稿编号 |
36408 |
| 手稿来源省、自治区或特别行政区 |
北京市 |
| 专业类型 |
消化基础研究 |
| 手稿栏目类型 |
述评 |
| 文章标题 |
慢加急性肝衰竭研究的新视角: 肝纤维化与损伤抵抗
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| 手稿来源 |
约稿 |
| 所有作者列表 |
白丽, 陈煜, 段钟平, 郑素军 |
| 基金项目及其编号 |
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| 通讯作者 |
郑素军, 博士, 教授, 主任医师, 100069, 北京市丰台区右安门外西头条8号, 首都医科大学附属北京佑安医院疑难肝病与人工肝中心. zhengsujun003@126.com |
| 关键词 |
慢加急性肝衰竭; 肝纤维化; 损伤抵抗; 巨噬细胞活化; 表型转换 |
| 核心内容提要 |
纤维化肝脏中M2-样活化的巨噬细胞发挥着抵抗急性打击的有益肝保护效应, 其作用机制主要包括两个方面: (1)促进介导损伤效应的M1-样巨噬细胞凋亡, 抑制肝细胞凋亡; (2)抑制HMGB1的转位和释放及其介导的促炎免疫反应. 调控巨噬细胞的M1/M2活化有望成为控制慢加急性肝衰竭发展及影响疾病转归的重要策略. |
| 引文著录 |
白丽, 陈煜, 段钟平, 郑素军. 慢加急性肝衰竭研究的新视角: 肝纤维化与损伤抵抗. 世界华人消化杂志 2018 |
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Received |
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2018-09-21 09:19 |
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Peer-Review Started |
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2018-09-22 14:01 |
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To Make the First Decision |
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2018-10-11 02:56 |
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Return for Revision |
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2018-10-14 05:36 |
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修回稿 |
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2018-10-23 09:13 |
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Second Decision |
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2018-11-08 09:34 |
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期刊总编辑接受 |
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公司总编辑接受 |
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2018-11-09 00:18 |
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预出版 |
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2018-11-09 00:18 |
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缴纳版面费 |
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Edit the Manuscript by Language Editor |
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排版 |
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2019-01-28 11:14 |
| ISSN |
1009-3079 (print) and 2219-2859 (online) |
| 开放获取 |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| 版权 |
© The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| 网址 |
http://www.wjgnet.com |
| Assistant Editor |
李香 |
| Science Editor |
崔丽君 |
| 评议人编号 |
02540663, 03552492, and 03202804 |
| Editorial Director |
马亚娟 |
| Journal Chief Editor |
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| Company Chief Editor |
马连生 |
| Language Editor |
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| Production Editor |
张砚梁 |
| Responsible Production Editor |
张砚梁 |
| Responsible Science Editor |
崔丽君 |
| Proofing Editorial Director |
Jin-Lei Wang |
| Proofing Editor-in-Chief |
Lian-Sheng Ma |
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