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2019/6/5 18:09:44 | Browse: 185 | 下载: 200
Publication Name 世界华人消化杂志
手稿编号 36925
手稿来源省、自治区或特别行政区 浙江省
专业类型 消化基础研究
手稿栏目类型 基础研究
文章标题 下调miRNA-214表达抑制胃癌SGC-7901/DDP细胞顺铂耐药、迁移和上皮间质转化
手稿来源 自由来稿
所有作者列表 朱艳, 刘玮丽, 吴明东, 庄永卫, 叶淑芳, 施旭红
基金项目及其编号
基金项目名称 基金编号
2015年丽水市科技局基金项目 2015zdxk07
通讯作者 刘玮丽, 博士, 副主任医师, 310000, 杭州市庆春东路3号, 邵逸夫医院消化内科. liuweilillpp23@aliyun.com
关键词 miR-214; 胃癌; 上皮间质转化; 顺铂耐药
核心内容提要 铂类药物为主的化疗是治疗胃癌的常用手段之一, 而化疗耐药制约着化疗的最终疗效. 本研究发现, 下调SGC-7901/DDP细胞miR-214表达后, 顺铂耐药性、细胞迁移与上皮间质转化均降低; 同时, NF-κB与Bcl-2的表达也明显降低.
引文著录 朱艳, 刘玮丽, 吴明东, 庄永卫, 叶淑芳, 施旭红. 下调miRNA-214表达抑制胃癌SGC-7901/DDP细胞顺铂耐药、迁移和上皮间质转化. 世界华人消化杂志 2019
Received
2019-04-11 03:29
Peer-Review Started
2019-04-12 00:21
To Make the First Decision
2019-04-17 07:27
Return for Revision
2019-04-23 08:51
修回稿
2019-05-14 06:37
Second Decision
2019-05-31 09:22
期刊总编辑接受
公司总编辑接受
2019-06-05 18:09
预出版
2019-06-05 18:09
缴纳版面费
Edit the Manuscript by Language Editor
排版
2019-06-27 05:28
ISSN 1009-3079 (print) and 2219-2859 (online)
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