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预出版
2019/9/3 17:43:54 | Browse: 289 | 下载: 235
Publication Name |
世界华人消化杂志 |
手稿编号 |
37159 |
手稿来源省、自治区或特别行政区 |
上海市 |
专业类型 |
消化外科学 |
手稿栏目类型 |
述评 |
文章标题 |
肝细胞癌切除术后复发的原因与防治策略
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手稿来源 |
约稿 |
所有作者列表 |
秦建民 |
基金项目及其编号 |
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通讯作者 |
秦建民, 博士, 教授, 主任医师, 201805, 上海市嘉定区墨玉北路700号, 海军军医大学附属第三医院普外科. jianminqin@yahoo.com |
关键词 |
肝细胞癌; 复发; 原因; 治疗; 预防 |
核心内容提要 |
肝细胞癌术后复发是一个多步骤、多环节的复杂过程,涉及机体、微环境和肿瘤组织三个方面因素,包括机体免疫力、局部PH值、间质压力、血管渗透压、炎性反应、肿瘤细胞黏附、细胞外基质降解、细胞迁移、细胞增殖和肿瘤血管形成等,与多个基因表达异常和相关分子功能改变密切相关。肝细胞癌术后复发治疗涉及再次手术、肝移植、局部微创治疗、放疗、分子靶向药物、免疫和中医药治疗,针对患者的具体情况,采取个体化的治疗方案,选择合适的治疗方法是提高疗效的关键。对于存在高危复发因素的肝癌患者,术后选择适当的治疗方法预防肝癌复发,是降低肝癌术后复发率,延长患者生存期的重要措施,才能使术后肝癌患者最大程度获益。 |
引文著录 |
秦建民. 肝细胞癌切除术后复发的原因与防治策略. 世界华人消化杂志 2019 |
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Received |
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2019-08-02 01:29 |
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Peer-Review Started |
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2019-08-05 06:43 |
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To Make the First Decision |
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2019-08-20 06:19 |
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Return for Revision |
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2019-08-21 07:22 |
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修回稿 |
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2019-09-02 03:23 |
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Second Decision |
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2019-09-03 05:36 |
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期刊总编辑接受 |
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公司总编辑接受 |
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2019-09-03 17:43 |
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预出版 |
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2019-09-03 17:43 |
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缴纳版面费 |
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Edit the Manuscript by Language Editor |
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排版 |
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2019-12-06 08:30 |
ISSN |
1009-3079 (print) and 2219-2859 (online) |
开放获取 |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
版权 |
© The Author(s) 2019 Published by Baishideng Publishing Group Inc. All rights reserved. |
Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
网址 |
http://www.wjgnet.com |
Assistant Editor |
李香 |
Science Editor |
王禹乔 |
评议人编号 |
03270509, 02947240, and 02936110 |
Editorial Director |
马亚娟 |
Journal Chief Editor |
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Company Chief Editor |
马俐 |
Language Editor |
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Production Editor |
Ji-Hong Liu |
Responsible Production Editor |
Ji-Hong Liu |
Responsible Science Editor |
马亚娟 |
Proofing Editorial Director |
Jin-Lei Wang |
Proofing Editor-in-Chief |
Lian-Sheng Ma |
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