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预出版
2020/6/24 1:32:27 | Browse: 210 | 下载: 339
| Publication Name |
世界华人消化杂志 |
| 手稿编号 |
37642 |
| 手稿来源省、自治区或特别行政区 |
江西省 |
| 专业类型 |
消化基础研究 |
| 手稿栏目类型 |
基础研究 |
| 文章标题 |
二甲双胍增强索拉菲尼诱导HepG2细胞凋亡的分子机制
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| 手稿来源 |
自由来稿 |
| 所有作者列表 |
叶艳清, 曾斌, 廖跃光, 刘茂生, 华宗荣 |
| 基金项目及其编号 |
| 基金项目名称 |
基金编号 |
| 江西省卫生健康委科技计划资助项目 |
20201084 |
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| 通讯作者 |
叶艳清, 主治医师, 341000, 江西省赣州市青年路23号, 赣南医学院第一附属医院消化内科. gnmu2002@126.com |
| 关键词 |
二甲双胍; 索拉菲尼; HepG2细胞; 分子机制 |
| 核心内容提要 |
索拉菲尼是唯一推荐于治疗晚期肝癌的靶向药物, 但耐药是一个恼人的问题! 二甲双胍近年来广泛被报道可以抑制肿瘤增殖、诱导凋亡, 且在临床上可以改善肿瘤病人的预后. 本文就是通过二者的联合作用, 观察其联合对HepG2细胞凋亡的影响及分子机制. |
| 引文著录 |
叶艳清, 曾斌, 廖跃光, 刘茂生, 华宗荣. 二甲双胍增强索拉菲尼诱导HepG2细胞凋亡的分子机制. 世界华人消化杂志 2020 |
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Received |
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2020-03-24 01:20 |
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Peer-Review Started |
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2020-03-24 11:35 |
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To Make the First Decision |
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Return for Revision |
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2020-05-29 18:42 |
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修回稿 |
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2020-06-19 11:29 |
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Second Decision |
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2020-06-23 07:39 |
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期刊总编辑接受 |
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公司总编辑接受 |
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2020-06-24 01:32 |
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预出版 |
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2020-06-24 01:32 |
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缴纳版面费 |
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Edit the Manuscript by Language Editor |
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排版 |
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2020-07-27 06:14 |
| ISSN |
1009-3079 (print) and 2219-2859 (online) |
| 开放获取 |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| 版权 |
© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| 网址 |
http://www.wjgnet.com |
| Assistant Editor |
王栋梅 |
| Science Editor |
张晗 |
| 评议人编号 |
03656580 |
| Editorial Director |
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| Journal Chief Editor |
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| Company Chief Editor |
马连生 |
| Language Editor |
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| Production Editor |
Ji-Hong Liu |
| Responsible Production Editor |
Ji-Hong Liu |
| Responsible Science Editor |
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| Proofing Editorial Director |
Jin-Lei Wang |
| Proofing Editor-in-Chief |
Lian-Sheng Ma |
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