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Publication Name 世界华人消化杂志
手稿编号 37814
手稿来源省、自治区或特别行政区 山东省
专业类型 消化内科学
手稿栏目类型 述评
文章标题 非酒精性脂肪性胰病研究现状与进展
手稿来源 约稿
所有作者列表 池肇春
基金项目及其编号
通讯作者 池肇春, 教授, 主任医师, 266011, 山东省青岛市胶州路1号, 青岛市市立医院消化内科. c.z.chow@163.com
关键词 非酒精性脂肪性胰病; 发病机制; 影像诊断; 展望; ;
核心内容提要 非酒精性脂肪性胰病(nonalcoholic fatty pancreatic disease, NAFPD)是近几年来被人们重视和开展广泛研究的一种代谢疾病, 研究证据表明除与胰腺本身疾病相关外, 与NAFLD、肝纤维化、肝炎、肝癌、心血管疾病、肿瘤等密切相关, 对其他系统疾病的发生和影响目前知之甚少. NAFPD人群流行率高达11%-69%, 尤其肥胖儿童比非肥胖儿童发病率高2倍多, 值得重视. 有关NAFPD 的发病机制尚未完全明了, 目前认为与肥胖、胰岛素抵抗、表观遗传和遗传倾向、氧化应激和内质网(endoplasmic reticulum, ER)应激、肠道微生物等有关. B超瞬时弹性成像和磁共振质子密度脂肪分数是目前最常用无创有效的胰腺脂肪诊断方法. 合理饮食、改变生活方式、加强体育锻炼是NAFPD当前最有效的治疗方法, 目前 对NAFPD 尚无特效的药物治疗.
引文著录 池肇春. 非酒精性脂肪性胰病研究现状与进展. 世界华人消化杂志 2020; 28(19): 933-950
Received
2020-06-08 01:08
Peer-Review Started
2020-06-09 07:51
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Return for Revision
2020-06-24 01:42
修回稿
2020-07-02 12:16
Second Decision
2020-07-14 11:10
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2020-07-15 13:19
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2020-07-15 13:19
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排版
2020-09-28 10:32
ISSN 1009-3079 (print) and 2219-2859 (online)
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