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Publication Name 世界华人消化杂志
手稿编号 37866
手稿来源省、自治区或特别行政区 江苏省
专业类型 消化内科学
手稿栏目类型 文献综述
文章标题 去整合素-金属蛋白酶17在消化系统恶性肿瘤中的研究现状
手稿来源 自由来稿
所有作者列表 徐榕, 康海锋, 刘宏斌, 钱俊波
基金项目及其编号
基金项目名称 基金编号
南通市卫生和计划生育委员会科研课题专项 MB2019004
通讯作者 钱俊波, 研究生, 副教授, 主任医师, 226000, 江苏省南通市孩儿巷北路6号, 通大学第二附属医院消化内科. ntyyqjb@163.com
关键词 去整合素-金属蛋白酶17; 肿瘤坏死因子α转换酶; 消化系统; 恶性肿瘤; ;
核心内容提要 去整合素-金属蛋白酶17(a disintegrin and metalloproteinase 17, ADAM17)为关键的裂解酶, 不仅在细胞增殖、血管生成等过程中发挥作用; 还可以通过降解细胞基底膜和细胞外基质, 与细胞侵袭、转移能力密切相关, 因此在许多恶性肿瘤中表达上调. ADAM17在消化系统恶性肿瘤中也有报道, 但实质性进展远未阐明.
引文著录 徐榕, 康海锋, 刘宏斌, 钱俊波. 去整合素-金属蛋白酶17在消化系统恶性肿瘤中的研究现状. 世界华人消化杂志 2020; 28(19): 986-991
Received
2020-07-15 01:15
Peer-Review Started
2020-07-15 09:12
To Make the First Decision
Return for Revision
2020-07-30 18:01
修回稿
2020-08-16 08:03
Second Decision
2020-08-27 22:40
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2020-08-31 04:27
预出版
2020-08-31 04:27
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2020-09-28 10:39
ISSN 1009-3079 (print) and 2219-2859 (online)
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