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2021/7/7 15:42:32 | Browse: 157 | 下载: 232
| Publication Name |
世界华人消化杂志 |
| 手稿编号 |
38372 |
| 手稿来源省、自治区或特别行政区 |
广西壮族自治区 |
| 专业类型 |
消化感染病学 |
| 手稿栏目类型 |
基础研究 |
| 文章标题 |
HBV 1.3倍基因组HepG2稳转细胞模型优势单克隆株的筛选及鉴定
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| 手稿来源 |
自由来稿 |
| 所有作者列表 |
邱华, 林栋毅, 李锦源 |
| 基金项目及其编号 |
| 基金项目名称 |
基金编号 |
| 国家自然科学基金项目 |
81860889 |
| 国家自然科学基金项目 |
81660827 |
| 中国博士后科学基金面上项目 |
2019M653312 |
| 广西自然科学基金面上项目 |
2020GXNSFAA297113 |
| 广西科技厅重点研发项目 |
2017AB45166 |
| 第二批广西高层次骨干人才培养139计划 |
桂卫科教发[2018]22号 |
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| 通讯作者 |
邱华, 博士, 教授, 530021, 南宁市青秀区河堤路7号, 广西医科大学附属肿瘤医院中医科. qiuhua8899@163.com |
| 关键词 |
乙型肝炎病毒; 1.3倍基因组; 稳转; 细胞模型; 优势单克隆 |
| 核心内容提要 |
成功构建并筛选出乙型肝炎病毒(hepatitis B virus, HBV)1.3倍基因组HepG2稳转细胞模型优势单克隆株HepGA14，其能稳定、高效地表达共价闭合环状DNA分子(covalently closed circularDNA, cccDNA)、乙型肝炎病毒X蛋白(hepatitis B virus X protein, HBx)、HBVDNA、HBsAg、HBeAg等生物标志物，有望在研制乙肝“治愈”药物及探索HBV相关疾病发病机制等领域发挥积极作用. |
| 引文著录 |
邱华, 林栋毅, 李锦源. HBV 1.3倍基因组HepG2稳转细胞模型优势单克隆株的筛选及鉴定. 世界华人消化杂志 2021; 29(16): 934-944 |
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Received |
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2021-05-28 00:23 |
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Peer-Review Started |
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2021-05-29 03:28 |
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To Make the First Decision |
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Return for Revision |
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2021-06-14 14:04 |
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修回稿 |
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2021-06-16 04:12 |
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Second Decision |
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2021-07-06 01:29 |
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期刊总编辑接受 |
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公司总编辑接受 |
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2021-07-07 15:42 |
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预出版 |
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2021-07-07 15:42 |
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缴纳版面费 |
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Edit the Manuscript by Language Editor |
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排版 |
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2021-08-29 00:19 |
| ISSN |
1009-3079 (print) and 2219-2859 (online) |
| 开放获取 |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| 版权 |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| 网址 |
http://www.wjgnet.com |
| Assistant Editor |
张砚梁 |
| Science Editor |
张砚梁 |
| 评议人编号 |
03656599, 03656412, and 03200185 |
| Editorial Director |
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| Journal Chief Editor |
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| Company Chief Editor |
马俐 |
| Language Editor |
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| Production Editor |
张砚梁 |
| Responsible Production Editor |
张砚梁 |
| Responsible Science Editor |
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| Proofing Editorial Director |
Jin-Lei Wang |
| Proofing Editor-in-Chief |
Lian-Sheng Ma |
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