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预出版
2023/9/26 20:04:33 | Browse: 106 | 下载: 0
| Publication Name |
世界华人消化杂志 |
| 手稿编号 |
39569 |
| 手稿来源省、自治区或特别行政区 |
浙江省 |
| 专业类型 |
消化内科学 |
| 手稿栏目类型 |
临床实践 |
| 文章标题 |
解整合素-金属蛋白酶33基因多态性与胆管癌及血清肿瘤标志物水平的相关性研究
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| 手稿来源 |
自由来稿 |
| 所有作者列表 |
邱雷, 危贵君 |
| 基金项目及其编号 |
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| 通讯作者 |
邱雷, 本科, 主任药师, 主治医师, 313000, 湖州市吴兴区广场后路158号湖州市第一人民医院2号楼消化内科, 湖州市第一人民医院消化内科. azrsml0451@163.com |
| 关键词 |
胆管癌; 解整合素-金属蛋白酶33; 单核苷酸多态性; 易感性 |
| 核心内容提要 |
目前认为胆管癌(cholangiocarcinoma, CC)的发病与肝炎、糖尿病、吸烟、饮酒、基因多态性、肥胖等多种因素有关. 研究发现, 胆管癌组织中(disintegrin and metalloproteinase, ADAM)33蛋白表达显著升高, 且与预后不良有关. ADAM33 rs678881 GC、CC基因型及C等位基因增加胆管癌的易感性及血清肿瘤标志物的水平, 可能参与了CC的病理进程. |
| 引文著录 |
邱雷, 危贵君. 解整合素-金属蛋白酶33基因多态性与胆管癌及血清肿瘤标志物水平的相关性研究. 世界华人消化杂志 2023; 31(20): 871-876 |
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Received |
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2023-07-22 09:09 |
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Peer-Review Started |
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2023-07-22 09:19 |
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To Make the First Decision |
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Return for Revision |
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2023-09-02 18:38 |
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修回稿 |
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2023-09-08 01:53 |
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Second Decision |
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2023-09-26 13:26 |
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期刊总编辑接受 |
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公司总编辑接受 |
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2023-09-26 20:04 |
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预出版 |
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2023-09-26 20:04 |
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缴纳版面费 |
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Edit the Manuscript by Language Editor |
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排版 |
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2023-10-27 08:44 |
| ISSN |
1009-3079 (print) and 2219-2859 (online) |
| 开放获取 |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| 版权 |
© The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| 网址 |
http://www.wjgnet.com |
| Assistant Editor |
张砚梁 |
| Science Editor |
张砚梁 |
| 评议人编号 |
03656403, 03213109, and 02936110 |
| Editorial Director |
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| Journal Chief Editor |
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| Company Chief Editor |
马俐 |
| Language Editor |
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| Production Editor |
张砚梁 |
| Responsible Production Editor |
张砚梁 |
| Responsible Science Editor |
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| Proofing Editorial Director |
Jin-Lei Wang |
| Proofing Editor-in-Chief |
Lian-Sheng Ma |
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