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2024/4/15 1:31:14 | Browse: 13 | 下载: 0
| Publication Name |
世界华人消化杂志 |
| 手稿编号 |
39869 |
| 手稿来源省、自治区或特别行政区 |
江苏省 |
| 专业类型 |
消化感染病学 |
| 手稿栏目类型 |
文献综述 |
| 文章标题 |
乙型肝炎表面抗原泛素化修饰的研究进展
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| 手稿来源 |
约稿 |
| 所有作者列表 |
牛安行, 刘锦, 朱传武 |
| 基金项目及其编号 |
| 基金项目名称 |
基金编号 |
| 国家自然科学基金项目 |
No. 82172252和No.82002194 |
| 江苏省自然科学基金项目 |
No. BK20211080 |
| 苏州姑苏卫生人才计划项目 |
No. GSWS2020091 |
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| 通讯作者 |
朱传武, 博士, 教授, 主任医师, 215131, 苏州市相城区广前路10号, 苏州市第五人民医院，苏州大学附属传染病医院感染、肝病科. zhuchw@126.com |
| 关键词 |
乙型肝炎表面抗原; 泛素化; 类泛素化; 去泛素化 |
| 核心内容提要 |
慢性乙型肝炎病毒(hepatitis B virus, HBV)感染的主要原因之一是由于患者体内存在大量血清乙型肝炎表面抗原(hepatitis B surface antigen, HBsAg), 导致患者特异性免疫功能下降, 病毒难以被清除. HBsAg的泛素化修饰和降解, 有可能改变患者体内HBV的生存和免疫环境, 因此, 加强该领域的研究, 有可能开发出新的药物, 以增加实现功能性治愈的机会. |
| 引文著录 |
牛安行, 刘锦, 朱传武. 乙型肝炎表面抗原泛素化修饰的研究进展. 世界华人消化杂志 2024 |
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Received |
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2024-02-26 08:45 |
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Peer-Review Started |
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2024-02-26 09:59 |
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To Make the First Decision |
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Return for Revision |
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2024-04-01 00:40 |
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修回稿 |
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2024-04-06 14:19 |
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Second Decision |
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2024-04-12 08:19 |
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期刊总编辑接受 |
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公司总编辑接受 |
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2024-04-15 01:31 |
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预出版 |
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2024-04-15 01:31 |
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缴纳版面费 |
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Edit the Manuscript by Language Editor |
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排版 |
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| ISSN |
1009-3079 (print) and 2219-2859 (online) |
| 开放获取 |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| 版权 |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| 网址 |
http://www.wjgnet.com |
| Assistant Editor |
吴云晓健 |
| Science Editor |
张砚梁 |
| 评议人编号 |
03206549, 03656412, 03656515, and 03656599 |
| Editorial Director |
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| Journal Chief Editor |
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| Company Chief Editor |
闫佳萍 |
| Language Editor |
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| Production Editor |
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| Responsible Production Editor |
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| Responsible Science Editor |
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| Proofing Editorial Director |
Jin-Lei Wang |
| Proofing Editor-in-Chief |
Lian-Sheng Ma |
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