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预出版
2025/5/8 2:00:39 | Browse: 6 | 下载: 0
| Publication Name |
世界华人消化杂志 |
| 手稿编号 |
40201 |
| 手稿来源省、自治区或特别行政区 |
浙江省 |
| 专业类型 |
消化基础研究 |
| 手稿栏目类型 |
基础研究 |
| 文章标题 |
荷花碱通过抑制氧化应激与炎症反应减轻酒精诱导的小鼠肝损伤
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| 手稿来源 |
自由来稿 |
| 所有作者列表 |
蘧小红, 刘晓君 |
| 基金项目及其编号 |
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| 通讯作者 |
蘧小红, 本科, 主管技师, 321200, 武义第一人民医院检验科, 武义第一人民医院检验科. 13566939720@163.com |
| 关键词 |
荷花碱; 酒精性肝损伤; 氧化应激; 炎症反应; Nrf-2/HO-1; NF-κB |
| 核心内容提要 |
荷花碱(neferine, NeF)作为一种有效的抗氧化剂和抗炎剂, 可以抑制酒精性肝损伤(alcoholic liver injury, ALI)小鼠肝脏中的氧化和炎症现象. 尽管本研究揭示了NeF的多重保护机制, 仍需进一步探讨其生物利用度及组织特异性分布. 未来研究可结合基因敲除模型验证关键信号节点的作用, 并通过结构修饰优化其药代动力学特性, 为其在ALI临床应用奠定基础. |
| 引文著录 |
蘧小红, 刘晓君. 荷花碱通过抑制氧化应激与炎症反应减轻酒精诱导的小鼠肝损伤.世界华人消化杂志 2025 |
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Received |
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2025-02-27 04:43 |
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Peer-Review Started |
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2025-03-05 01:17 |
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To Make the First Decision |
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Return for Revision |
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2025-04-15 01:53 |
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修回稿 |
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2025-04-16 08:28 |
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Second Decision |
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2025-05-07 09:06 |
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期刊总编辑接受 |
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公司总编辑接受 |
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2025-05-08 02:00 |
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预出版 |
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2025-05-08 02:00 |
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缴纳版面费 |
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Edit the Manuscript by Language Editor |
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排版 |
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| ISSN |
1009-3079 (print) and 2219-2859 (online) |
| 开放获取 |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| 版权 |
©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| 网址 |
http://www.wjgnet.com |
| Assistant Editor |
吴云晓健 |
| Science Editor |
刘继红 |
| 评议人编号 |
03656580, 03317130, 03741371, 03455867, and 03307686 |
| Editorial Director |
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| Journal Chief Editor |
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| Company Chief Editor |
闫佳萍 |
| Language Editor |
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| Production Editor |
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| Responsible Production Editor |
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| Responsible Science Editor |
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| Proofing Editorial Director |
Jin-Lei Wang |
| Proofing Editor-in-Chief |
Lian-Sheng Ma |
© 2004-2022 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
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