BPG致力于知识发现和传播
预出版
2025/8/18 1:22:34 | Browse: 9 | 下载: 0
| Publication Name |
世界华人消化杂志 |
| 手稿编号 |
40291 |
| 手稿来源省、自治区或特别行政区 |
天津市 |
| 专业类型 |
消化内科学 |
| 手稿栏目类型 |
文献综述 |
| 文章标题 |
巴雷特食管致病因素与相关信号转导通路的研究进展
|
| 手稿来源 |
自由来稿 |
| 所有作者列表 |
李思琪, 杨磊, 李培彩, 弓艳霞 |
| 基金项目及其编号 |
|
| 通讯作者 |
弓艳霞, 博士, 主任医师, 300100, 南开三纬路122号, 天津市南开医院消化内科. gong_yanxia@aliyun.com |
| 关键词 |
巴雷特食管; 发病机制; 信号转导通路; 致病因素 |
| 核心内容提要 |
巴雷特食管为胃食管反流病常见的并发症之一, 因其显著的食管腺癌转化风险, 始终是临床与科研领域的焦点. 其病理演变涉及食管鳞状上皮被异常柱状上皮取代, 部分患者还伴随肠上皮化生, 这一过程的分子机制极为复杂, 涵盖多条信号传导通路的异常激活与调控失衡. 近年来在细胞分子生物学层面的研究不断深入, 但确切的发病机制仍存在诸多未知领域. 目前对于巴雷特食管的防治, 部分中药复方或单体成分经临床实践与基础研究证实, 能够有效抑制柱状上皮化生进程, 甚至逆转早期病变, 现阐述巴雷特食管的发病机制, 深入分析所涉及的包含胃酸与胆汁酸为主的致病因素, 及包含炎症与化生相关的分子信号通路, 为未来研制有效的化学预防药物提供线索. |
| 引文著录 |
李思琪, 杨磊, 李培彩, 弓艳霞. 巴雷特食管致病因素与相关信号转导通路的研究进展. 世界华人消化杂志 2025 |
 |
Received |
|
2025-05-20 02:25 |
|
Peer-Review Started |
|
2025-05-20 09:13 |
 |
To Make the First Decision |
|
|
|
Return for Revision |
|
2025-06-20 01:45 |
|
修回稿 |
|
2025-06-24 10:04 |
|
Second Decision |
|
2025-08-13 07:49 |
|
期刊总编辑接受 |
|
|
|
公司总编辑接受 |
|
2025-08-18 01:22 |
|
预出版 |
|
2025-08-18 01:22 |
|
缴纳版面费 |
|
|
|
Edit the Manuscript by Language Editor |
|
|
|
排版 |
|
|
| ISSN |
1009-3079 (print) and 2219-2859 (online) |
| 开放获取 |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| 版权 |
©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| 网址 |
http://www.wjgnet.com |
| Assistant Editor |
吴云晓健 |
| Science Editor |
刘继红 |
| 评议人编号 |
03203171, 02546910, 03089986, and 03770580 |
| Editorial Director |
|
| Journal Chief Editor |
|
| Company Chief Editor |
闫佳萍 |
| Language Editor |
|
| Production Editor |
|
| Responsible Production Editor |
|
| Responsible Science Editor |
|
| Proofing Editorial Director |
Jin-Lei Wang |
| Proofing Editor-in-Chief |
Lian-Sheng Ma |
© 2004-2022 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
California Corporate Number: 3537345
