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Publication Name 世界华人消化杂志
手稿编号 40498
手稿来源省、自治区或特别行政区 江苏省
专业类型 消化内科学
手稿栏目类型 述评
文章标题 不确定期慢性HBV感染的研究进展
手稿来源 约稿
所有作者列表 张福奎
基金项目及其编号
通讯作者 张福奎, 博士, 主任医师, 210019, 河西大街71号, 南京医科大学附属明基医院消化内科. frankliver@163.com
关键词 慢性乙型肝炎病毒感染; 不确定期/灰区; 丙氨酸氨基转移酶; 肝细胞癌; 抗病毒治疗
核心内容提要 不确定期在慢性乙型肝炎病毒(hepatitis B virus, HBV)感染患者中临床占比极高, 约半数不确定期患者合并肝脏显著组织学改变, 疾病进展及肝细胞癌(hepatocellular carcinoma, HCC)发生风险显著升高. 对高危不确定期患者及时启动抗病毒治疗, 可有效降HCC及肝硬化发生风险. 未来, 依托新型生物标志物与评分模型精准识别高危人群, 构建更优化的分层管理策略, 将成为慢性HBV感染防治领域的重要研究方向.
引文著录 张福奎. 不确定期慢性HBV感染的研究进展. 世界华人消化杂志 2026
Received
2026-03-05 05:57
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2026-03-05 07:11
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2026-03-24 12:33
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2026-04-13 05:54
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2026-04-23 08:02
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2026-04-24 09:22
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