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2026/8/6 3:33:43 | Browse: 6 | 下载: 0
| Publication Name |
世界华人消化杂志 |
| 手稿编号 |
40635 |
| 手稿来源省、自治区或特别行政区 |
陕西省 |
| 专业类型 |
消化肿瘤学 |
| 手稿栏目类型 |
文献综述 |
| 文章标题 |
C2H2型锌指蛋白在肝细胞癌发生发展中的作用
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| 手稿来源 |
约稿 |
| 所有作者列表 |
王怡恺, 党双锁 |
| 基金项目及其编号 |
| 基金项目名称 |
基金编号 |
| 四大慢病重大专项 |
2024ZD0526200 |
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| 通讯作者 |
党双锁, 博士, 教授, 主任医师, 710004, 陕西省西安市新城区西五路157号, 西安交通大学第二附属医院感染科. dang212@126.com |
| 关键词 |
肝细胞癌; C2H2型锌指蛋白; 生物标志物; 诊断; 预后 |
| 核心内容提要 |
锌指蛋白(zinc finger proteins, ZNF)在肝细胞癌(hepatocellular carcinoma, HCC)发生发展中具有显著的双重性. 当前研究热点已从单纯识别异常表达, 转向机制干预: 即靶向抑制促癌ZNF, 或恢复抑癌ZNF功能. 未来趋势是开发基于ZNFs的联合疗法, 以克服肿瘤耐药性, 实现HCC的精准诊断和治疗. |
| 引文著录 |
王怡恺, 党双锁. C2H2型锌指蛋白在肝细胞癌发生发展中的作用. 世界华人消化杂志 2026 |
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Received |
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2026-06-04 09:14 |
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Peer-Review Started |
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2026-06-05 06:04 |
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To Make the First Decision |
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Return for Revision |
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2026-07-03 12:43 |
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修回稿 |
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2026-07-10 03:45 |
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Second Decision |
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2026-07-30 08:37 |
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期刊总编辑接受 |
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公司总编辑接受 |
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2026-08-06 03:33 |
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预出版 |
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2026-08-06 03:33 |
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缴纳版面费 |
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Edit the Manuscript by Language Editor |
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排版 |
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| ISSN |
1009-3079 (print) and 2219-2859 (online) |
| 开放获取 |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| 版权 |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| 网址 |
http://www.wjgnet.com |
| Assistant Editor |
宣佳琪 |
| Science Editor |
刘继红 |
| 评议人编号 |
03656583, and 02997233 |
| Editorial Director |
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| Journal Chief Editor |
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| Company Chief Editor |
樊佳茹 |
| Language Editor |
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| Responsible Production Editor |
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| Responsible Science Editor |
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| Proofing Editorial Director |
Jin-Lei Wang |
| Proofing Editor-in-Chief |
Lian-Sheng Ma |
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