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2026/8/28 11:47:54 | Browse: 29 | 下载: 0
| Publication Name |
世界华人消化杂志 |
| 手稿编号 |
40654 |
| 手稿来源省、自治区或特别行政区 |
云南省 |
| 专业类型 |
消化肿瘤学 |
| 手稿栏目类型 |
文献综述 |
| 文章标题 |
干扰素刺激基因15在消化系统恶性肿瘤中的作用机制及研究进展
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| 手稿来源 |
约稿 |
| 所有作者列表 |
沈鑫, 彭馨鋆, 唐嘉黛, 谢琳 |
| 基金项目及其编号 |
| 基金项目名称 |
基金编号 |
| 云南省“兴滇人才支持计划”名医项目 |
No. XDYC-MY-2022-0011 |
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| 通讯作者 |
谢琳, 博士, 教授, 主任医师, 650118, 云南省昆明市西山区昆州路519号, 昆明医科大学第三附属医院/北京大学肿瘤医院云南医院/云南省肿瘤医院消化肿瘤内科. xielinyanghan@163.com |
| 关键词 |
干扰素刺激基因15; 消化系统恶性肿瘤; 免疫调控; 肿瘤干细胞; 治疗抵抗 |
| 核心内容提要 |
消化系统恶性肿瘤具有起病隐匿、早期缺乏特异性表现及整体预后较差等特点, 严重影响患者生存结局, 因此探索具有高敏感性与特异性的肿瘤相关分子标志物, 对其早期识别及临床干预具有重要意义. 近年来研究表明, 干扰素刺激基因15(interferon-stimulated gene 15, ISG15)作为一种关键的干扰素诱导型泛素样修饰蛋白, 广泛参与消化系统恶性肿瘤的发生发展及治疗应答过程. 本文围绕ISG15在消化系统恶性肿瘤中的研究进展进行综述. |
| 引文著录 |
沈鑫, 彭馨鋆, 唐嘉黛, 谢琳. 干扰素刺激基因15在消化系统恶性肿瘤中的作用机制及研究进展. 世界华人消化杂志 2026 |
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Received |
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2026-06-25 09:18 |
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Peer-Review Started |
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2026-06-26 06:01 |
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To Make the First Decision |
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Return for Revision |
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2026-07-21 07:30 |
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修回稿 |
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2026-08-10 13:51 |
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Second Decision |
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2026-08-27 03:43 |
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期刊总编辑接受 |
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公司总编辑接受 |
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2026-08-28 11:47 |
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预出版 |
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2026-08-28 11:47 |
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| ISSN |
1009-3079 (print) and 2219-2859 (online) |
| 开放获取 |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
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©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
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http://www.wjgnet.com |
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| Science Editor |
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| Proofing Editorial Director |
Jin-Lei Wang |
| Proofing Editor-in-Chief |
Lian-Sheng Ma |
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