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Publication Name 世界华人消化杂志
手稿编号 40663
手稿来源省、自治区或特别行政区 内蒙古自治区
专业类型 消化外科学
手稿栏目类型 文献综述
文章标题 肝门部胆管癌转化治疗的现状与展望
手稿来源 约稿
所有作者列表 牛海鹏, 王石
基金项目及其编号
通讯作者 王石, 博士, 主任医师, 010010, 内蒙古自治区呼和浩特市昭乌达路20号, 内蒙古自治区人民医院肝胆胰脾外科. wangstone2011@163.com
关键词 肝门部胆管癌; 转化治疗; 联合治疗; 化疗; 免疫治疗
核心内容提要 肝门部胆管癌转化治疗以GC方案联合免疫(如durvalumab)、立体定向体放射治疗局部控瘤及HER2靶向治疗最具前景, 但疗效异质性、手术时机与患者意愿构成主要挑战. 亟需随机对照试验验证最佳方案, 建立统一可切除评估体系, 并探索程序性死亡配体-1、循环肿瘤DNA等生物标志物, 推动个体化精准转化.
引文著录 牛海鹏, 王石. 肝门部胆管癌转化治疗的现状与展望. 世界华人消化杂志 2026
Received
2026-06-25 09:17
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2026-06-26 05:58
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2026-07-21 07:24
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2026-07-31 10:00
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2026-08-14 00:20
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2026-08-18 09:26
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2026-08-18 09:26
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