BPG致力于知识发现和传播
预出版
2026/10/24 11:16:19 | Browse: 14 | 下载: 0
| Publication Name |
世界华人消化杂志 |
| 手稿编号 |
40706 |
| 手稿来源省、自治区或特别行政区 |
天津市 |
| 专业类型 |
消化肿瘤学 |
| 手稿栏目类型 |
文献综述 |
| 文章标题 |
染色体外DNA在消化系统肿瘤中的研究进展
|
| 手稿来源 |
约稿 |
| 所有作者列表 |
雷芸云, 汪卉阳, 仲威龙, 刘文天 |
| 基金项目及其编号 |
|
| 通讯作者 |
刘文天, 博士, 教授, 主任医师, 300052, 天津市和平区鞍山道154号, 天津医科大学总医院消化内科. lwentian64@163.com |
| 关键词 |
染色体外DNA; 小型染色体外环状DNA; ecDNA; eccDNA; 消化系统肿瘤; 基因组不稳定性; 癌基因扩增; 治疗耐药 |
| 核心内容提要 |
消化系统肿瘤长期暴露于胃酸、胆汁酸、饮食致癌物、病毒整合、慢性炎症及缺氧等刺激, 这些因素可诱导DNA双链断裂和错误修复, 为染色体外DNA/小型染色体外环状DNA(small extrachromosomal circular DNA, eccDNA)的形成、扩增和演化提供条件. 深入解析消化系统肿瘤的流行病学现状并探索eccDNA的生物学功能, 对于开发新型诊疗策略具有重要意义. |
| 引文著录 |
雷芸云, 汪卉阳, 仲威龙, 刘文天. 染色体外DNA在消化系统肿瘤中的研究进展. 世界华人消化杂志 2026 |
 |
Received |
|
2026-07-16 01:53 |
|
Peer-Review Started |
|
2026-07-16 07:32 |
 |
To Make the First Decision |
|
|
|
Return for Revision |
|
2026-08-14 09:35 |
|
修回稿 |
|
2026-08-31 09:15 |
|
Second Decision |
|
2026-10-23 08:57 |
|
期刊总编辑接受 |
|
|
|
公司总编辑接受 |
|
2026-10-24 11:16 |
|
预出版 |
|
2026-10-24 11:16 |
|
缴纳版面费 |
|
|
|
Edit the Manuscript by Language Editor |
|
|
|
排版 |
|
|
| ISSN |
1009-3079 (print) and 2219-2859 (online) |
| 开放获取 |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| 版权 |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| 网址 |
http://www.wjgnet.com |
| Assistant Editor |
左倩 |
| Science Editor |
刘继红 |
| 评议人编号 |
03210359, 03656445, and 03270326 |
| Editorial Director |
|
| Journal Chief Editor |
|
| Company Chief Editor |
樊佳茹 |
| Language Editor |
|
| Production Editor |
|
| Responsible Production Editor |
|
| Responsible Science Editor |
|
| Proofing Editorial Director |
Jin-Lei Wang |
| Proofing Editor-in-Chief |
Lian-Sheng Ma |
© 2004-2026 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
California Corporate Number: 3537345
