Publication Name	世界华人消化杂志
手稿编号	40498
手稿来源省、自治区或特别行政区	江苏省

Received	2026-03-05 05:57
Peer-Review Started	2026-03-05 07:11
To Make the First Decision
Return for Revision	2026-03-24 12:33
修回稿	2026-04-13 05:54
Second Decision	2026-04-23 08:02
期刊总编辑接受
公司总编辑接受	2026-04-24 09:22
预出版	2026-04-24 09:22
缴纳版面费
Edit the Manuscript by Language Editor
排版	2026-05-19 06:54
在线出版	2026-05-20 02:34

ISSN	1009-3079 (print) and 2219-2859 (online)
开放获取	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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专业类型	消化内科学
手稿栏目类型	述评
文章标题	不确定期慢性HBV感染的研究进展
手稿来源	约稿
所有作者列表	张福奎
基金项目及其编号
通讯作者	张福奎, 博士, 主任医师, 210019, 河西大街71号, 南京医科大学附属明基医院消化内科. frankliver@163.com
关键词	慢性乙型肝炎病毒感染; 不确定期/灰区; 丙氨酸氨基转移酶; 肝细胞癌; 抗病毒治疗
核心内容提要	不确定期在慢性乙型肝炎病毒(hepatitis B virus, HBV)感染患者中临床占比极高, 约半数不确定期患者合并肝脏显著组织学改变, 疾病进展及肝细胞癌(hepatocellular carcinoma, HCC)发生风险显著升高. 对高危不确定期患者及时启动抗病毒治疗, 可有效降HCC及肝硬化发生风险. 未来, 依托新型生物标志物与评分模型精准识别高危人群, 构建更优化的分层管理策略, 将成为慢性HBV感染防治领域的重要研究方向.
出版日期	2026-05-20 02:34
引文著录	张福奎. 不确定期慢性HBV感染的研究进展. 世界华人消化杂志 2026; 34(4): 283-288
URL	https://www.wjgnet.com/1009-3079/full/v34/i4/283.htm
DOI	https://dx.doi.org/10.11569/wcjd.v34.i4.283

Full Article (PDF)	WCJD-34-283-with-cover.pdf
审稿意见	WCJD-40498-Peer-review(s).pdf
科学编辑工作清单	WCJD-40498-Scientific editor work list.pdf