Publication Name	世界华人消化杂志
手稿编号	36305
手稿来源省、自治区或特别行政区	江苏省

Received	2018-08-18 09:07
Peer-Review Started	2018-08-20 06:01
To Make the First Decision	2018-09-06 08:43
Return for Revision	2018-09-10 07:54
修回稿	2018-09-20 13:08
Second Decision	2018-09-29 07:03
期刊总编辑接受
公司总编辑接受	2018-10-08 02:07
预出版	2018-10-08 02:07
缴纳版面费
Edit the Manuscript by Language Editor
排版	2018-12-14 06:03
在线出版	2018-12-18 06:40

ISSN	1009-3079 (print) and 2219-2859 (online)
开放获取	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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专业类型	消化基础研究
手稿栏目类型	述评
文章标题	环氧合酶和脂氧合酶的抗肿瘤作用机制
手稿来源	约稿
所有作者列表	朱小朝, 张拓
基金项目及其编号
通讯作者	朱小朝, 研究生, 副主任医师, 223800, 江苏省宿迁市宿支路120号, 宿迁市第一人民医院普外科. zhuxc05206@126.com
关键词	环氧合酶; 脂氧合酶; 环氧合酶和脂氧合酶双效抑制剂; 抗肿瘤机制
核心内容提要	研究表明, 环氧合酶(cyclooxygenase, COXs)-2及其代谢产物前列腺素以及脂氧合酶(lipoxygenase, LOXs)介导的花生四烯酸代谢产物白三烯和羟-6,8,11,14-二十碳四烯酸对多种肿瘤的发生发展有重要作用. 因此, 联合应用COXs-2抑制剂和LOXs抑制剂,特别是COXs-2和LOXs双效抑制剂的应用, 为抗肿瘤作用研究开辟了广阔的前景.
出版日期	2018-12-18 06:40
引文著录	朱小朝, 张拓. 环氧合酶和脂氧合酶的抗肿瘤作用机制. 世界华人消化杂志 2018
URL	https://www.wjgnet.com/1009-3079/full/v26/i35/2029.htm
DOI	https://dx.doi.org/10.11569/wcjd.v26.i35.2029

Full Article (PDF)	WCJD-26-2029.pdf
审稿意见	WCJD-36305-Peer-review(s).pdf
科学编辑工作清单	WCJD-36305-Scientific editor work list.pdf