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2019/1/8 8:50:13 | Browse: 785 | 下载: 776
Publication Name |
世界华人消化杂志 |
手稿编号 |
36372 |
手稿来源省、自治区或特别行政区 |
四川省 |
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Received |
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2018-09-12 07:53 |
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Peer-Review Started |
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2018-09-13 03:01 |
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To Make the First Decision |
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2018-09-18 09:18 |
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Return for Revision |
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2018-09-21 06:32 |
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修回稿 |
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2018-10-24 16:04 |
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Second Decision |
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2018-11-08 09:08 |
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期刊总编辑接受 |
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公司总编辑接受 |
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2018-11-09 00:21 |
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预出版 |
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2018-11-09 00:21 |
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缴纳版面费 |
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Edit the Manuscript by Language Editor |
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排版 |
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2019-01-04 09:31 |
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在线出版 |
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2019-01-08 08:50 |
ISSN |
1009-3079 (print) and 2219-2859 (online) |
开放获取 |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
版权 |
© The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
网址 |
http://www.wjgnet.com |
专业类型 |
消化肿瘤学 |
手稿栏目类型 |
述评 |
文章标题 |
胰腺癌免疫治疗的挑战与前景
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手稿来源 |
约稿 |
所有作者列表 |
朱世凯, 许甜, 汪瑞 |
ORCID |
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基金项目及其编号 |
基金项目名称 |
基金编号 |
国家自然科学基金资助项目 |
81402029 |
四川省卫生计生委员会科研课题 |
16PJ429 |
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通讯作者 |
朱世凯, 博士, 副教授, 副主任医师, 610072, 四川省成都市青羊区一环路西二段32号, 电子科技大学附属医院肝胆胰外科. zhushikai37@163.com |
关键词 |
胰腺癌; 免疫治疗; 免疫检查点; CAR-T疗法; 肿瘤疫苗 |
核心内容提要 |
研究表明胰腺癌高致死性归因于由免疫抑制微环境, T细胞浸润低和基因突变负荷低等因素驱动而获得的肿瘤免疫特权. 目前, 各种新的免疫治疗的手段如免疫检查点阻断剂, 过继性细胞疗法和肿瘤疫苗等已进入临床或临床前期阶段, 都有希望成为提高胰腺癌患者救治率的新治疗策略. |
出版日期 |
2019-01-08 08:50 |
引文著录 |
朱世凯, 许甜, 汪瑞. 胰腺癌免疫治疗的挑战与前景. 世界华人消化杂志 2018 |
URL |
https://www.wjgnet.com/1009-3079/full/v27/i1/6.htm |
DOI |
https://dx.doi.org/10.11569/wcjd.v27.i1.6 |
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