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2019/11/8 7:18:09 | Browse: 587 | 下载: 646
Publication Name 世界华人消化杂志
手稿编号 37172
手稿来源省、自治区或特别行政区 四川省
Received
2019-08-16 01:16
Peer-Review Started
2019-08-16 10:35
To Make the First Decision
2019-08-27 01:04
Return for Revision
2019-08-27 07:18
修回稿
2019-10-14 14:30
Second Decision
2019-10-25 09:20
期刊总编辑接受
公司总编辑接受
2019-10-28 03:02
预出版
2019-10-28 03:02
缴纳版面费
Edit the Manuscript by Language Editor
排版
2019-11-08 02:55
在线出版
2019-11-08 07:18
ISSN 1009-3079 (print) and 2219-2859 (online)
开放获取 This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
版权 © The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
网址 http://www.wjgnet.com
专业类型 消化内科学
手稿栏目类型 临床研究
文章标题 LncRNA ATB在胆汁淤积性肝病患者血清中的表达及意义
手稿来源 自由来稿
所有作者列表 张向华, 李进英, 高金生
基金项目及其编号
通讯作者 高金生, 研究生, 副主任医师, 637600, 南充市仪陇县金城镇普济路13号, 四川南充仪陇县人民医院肿瘤科. gaojsylxyy@163.com
关键词 LncRNA-ATB; 胆汁淤积性肝病; 临床意义; ; ;
核心内容提要 胆汁淤积性肝病(cholestatic liver disease, CSLD)病因复杂,发病机制有待深入阐明, 尚缺乏足够有效的治疗手段. 本研究通过检测CSLD患者与正常人群中血清长链非编码RNA(long non coding RNA, LncRNA)-ATB的差异表达, 分析其临床意义. 研究发现LncRNA-ATB在CSLD患者中血清中高表达; LncRNA-ATB的表达与病情及胆汁淤积的程度相关, 随着胆汁淤积程度的加重血清LncRNA-ATB的表达下降, LncRNA-ATB与TBA的量呈负相关关系. LncRNA-ATB的表达水平有望成为判断CSLD患者病情及预后的生物标志物.
出版日期 2019-11-08 07:18
引文著录 张向华, 李进英, 高金生. LncRNA-ATB在胆汁淤积性肝病患者血清中的表达及意义. 世界华人消化杂志 2019
URL https://www.wjgnet.com/1009-3079/full/v27/i21/1320.htm
DOI https://dx.doi.org/10.11569/wcjd.v27.i21.1320
Full Article (PDF) WCJD-27-1320.pdf
审稿意见 WCJD-37172-Peer-review(s).pdf
科学编辑工作清单 WCJD-37172-Scientific editor work list.pdf