Publication Name	世界华人消化杂志
手稿编号	37651
手稿来源省、自治区或特别行政区	江苏省

Received	2020-03-25 00:40
Peer-Review Started	2020-03-26 16:48
To Make the First Decision
Return for Revision	2020-05-14 21:24
修回稿	2020-06-09 13:08
Second Decision	2020-06-23 09:30
期刊总编辑接受
公司总编辑接受	2020-06-24 01:31
预出版	2020-06-24 01:31
缴纳版面费
Edit the Manuscript by Language Editor
排版	2020-07-27 07:00
在线出版	2020-07-28 06:43

ISSN	1009-3079 (print) and 2219-2859 (online)
开放获取	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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专业类型	消化肿瘤学
手稿栏目类型	文献综述
文章标题	免疫检查点抑制剂治疗原发性肝癌的临床研究进展
手稿来源	约稿
所有作者列表	张金枝, 马雨竹, 顾佳麟, 霍介格
ORCID	作者 ORCID Number 霍介格 http://orcid.org/0000-0002-0463-134X
基金项目及其编号
通讯作者	霍介格, 博士, 教授, 210002, 江苏省南京市红山路十字街100号, 南京中医药大学第三临床医学院, 江苏省中西医结合医院. huojiege@jsatcm.com
关键词	原发性肝癌; 免疫检查点抑制剂; PD-1/PD-L1; CTLA-4; 联合用药
核心内容提要	本文主要综述了肿瘤免疫应答机制, 免疫检查点抑制剂在原发性肝癌的应用, 联合治疗, 免疫治疗疗效生物标志物及免疫检查点抑制剂应用中遇到的挑战.
出版日期	2020-07-28 06:43
引文著录	张金枝, 马雨竹, 顾佳麟, 霍介格. 免疫检查点抑制剂治疗原发性肝癌的临床研究进展. 世界华人消化杂志 2020
URL	https://www.wjgnet.com/1009-3079/full/v28/i14/605.htm
DOI	https://dx.doi.org/10.11569/wcjd.v28.i14.605

Full Article (PDF)	WCJD-28-605.pdf
审稿意见	WCJD-37651-Peer-review(s).pdf
科学编辑工作清单	WCJD-37651-Scientific editor work list.pdf