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2020/9/18 9:54:35 | Browse: 364 | 下载: 577
Publication Name |
世界华人消化杂志 |
手稿编号 |
37848 |
手稿来源省、自治区或特别行政区 |
广西壮族自治区 |
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Received |
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2020-07-01 00:14 |
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Peer-Review Started |
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2020-07-01 00:31 |
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To Make the First Decision |
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Return for Revision |
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2020-07-15 13:48 |
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修回稿 |
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2020-07-20 16:35 |
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Second Decision |
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2020-08-13 16:12 |
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期刊总编辑接受 |
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公司总编辑接受 |
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2020-08-13 23:29 |
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预出版 |
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2020-08-13 23:29 |
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缴纳版面费 |
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Edit the Manuscript by Language Editor |
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排版 |
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2020-09-18 02:13 |
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在线出版 |
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2020-09-18 09:54 |
ISSN |
1009-3079 (print) and 2219-2859 (online) |
开放获取 |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
版权 |
© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
网址 |
http://www.wjgnet.com |
专业类型 |
消化基础研究 |
手稿栏目类型 |
文献综述 |
文章标题 |
肝细胞癌缺氧微环境中低氧诱导因子-1α促进癌细胞免疫逃逸及治疗耐受的发生机制
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手稿来源 |
自由来稿 |
所有作者列表 |
杨焕珍, 周喜汉 |
ORCID |
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基金项目及其编号 |
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通讯作者 |
周喜汉, 博士, 教授, 主任医师, 533000, 广西壮族自治区百色市中山二路18号, 右江民族医学院附属医院消化内科. zhxh1966@sohu.com |
关键词 |
肝细胞癌; 低氧诱导因子-1α; 缺氧微环境; 免疫逃逸; 发生机制 |
核心内容提要 |
在本文中, 我们将阐述在肝癌缺氧微环境中低氧诱导因子-1α通过调节代谢重编程、转录因子、阻遏物以及细胞因子参与的免疫调节通路以及自噬来促进肿瘤细胞逃避免疫损害, 并阐述抗肿瘤药物出现耐药性导致药效不佳的原因, 为肝细胞癌免疫治疗提供潜在的新靶点. |
出版日期 |
2020-09-18 09:54 |
引文著录 |
杨焕珍, 周喜汉. 肝细胞癌缺氧微环境中低氧诱导因子-1α对免疫调控的影响. 世界华人消化杂志 2020 |
URL |
https://www.wjgnet.com/1009-3079/full/v28/i18/904.htm |
DOI |
https://dx.doi.org/10.11569/wcjd.v28.i18.904 |
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