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2020/10/28 12:21:18 | Browse: 513 | 下载: 604
| Publication Name |
世界华人消化杂志 |
| 手稿编号 |
37856 |
| 手稿来源省、自治区或特别行政区 |
湖北省 |
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Received |
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2020-07-13 05:55 |
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Peer-Review Started |
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2020-07-13 07:36 |
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To Make the First Decision |
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Return for Revision |
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2020-07-30 18:06 |
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修回稿 |
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2020-08-13 02:02 |
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Second Decision |
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2020-09-18 08:29 |
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期刊总编辑接受 |
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公司总编辑接受 |
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2020-09-21 04:07 |
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预出版 |
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2020-09-21 04:07 |
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缴纳版面费 |
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Edit the Manuscript by Language Editor |
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排版 |
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2020-10-28 06:25 |
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在线出版 |
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2020-10-28 12:21 |
| ISSN |
1009-3079 (print) and 2219-2859 (online) |
| 开放获取 |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| 版权 |
©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| 网址 |
http://www.wjgnet.com |
| 专业类型 |
消化内科学 |
| 手稿栏目类型 |
文献综述 |
| 文章标题 |
生物节律与肝脏代谢
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| 手稿来源 |
自由来稿 |
| 所有作者列表 |
高文康, 舒艳芸, 叶进, 潘晓莉 |
| ORCID |
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| 基金项目及其编号 |
| 基金项目名称 |
基金编号 |
| 国家自然科学基金 |
81770582 |
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| 通讯作者 |
潘晓莉, 博士, 主治医师, 430022, 解放大道1277号, 华中科技大学同济医学院附属协和医院消化内科. pxiaoli@hotmail.com |
| 关键词 |
昼夜节律; 生物钟基因; 肝脏能量代谢; 代谢障碍; ; |
| 核心内容提要 |
肝脏作为全身新陈代谢的枢纽，其功能包括调节碳水化合物、脂肪、蛋白质的代谢，胆汁合成，造血凝血及解毒等多个方面。近年来研究证实，肝脏内进行的各色生理活动几乎都受到生物钟的控制，而生物节律的紊乱则会引起肝脏新陈代谢及相应功能的紊乱，严重时可发展为代谢性疾病。随着现代生活节奏加快，工作休息节律与生理节律的去同步化已成常态，相关代谢疾病的发病率逐年攀升并呈年轻化趋势，故深入研究生物节律与肝脏代谢显得十分必要。本文结合近几年的相关科学报道，主要介绍了肝脏生物节律的来源和调控机制，总结了生理和病理条件下肝脏生物节律的变化，重点阐述了他们在调节葡萄糖、脂质、胆汁酸等代谢过程中所发挥的作用以及对某些疾病发生发展的潜在影响。 |
| 出版日期 |
2020-10-28 12:21 |
| 引文著录 |
高文康, 舒艳芸, 叶 进, 潘晓莉. 生物节律与肝脏能量代谢. 世界华人消化杂志 2020; 28(20): 1025-1035 |
| URL |
https://www.wjgnet.com/1009-3079/full/v28/i20/1025.htm |
| DOI |
https://dx.doi.org/10.11569/wcjd.v28.i20.1025 |
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