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2021/3/1 11:10:12 | Browse: 404 | 下载: 597
| Publication Name |
世界华人消化杂志 |
| 手稿编号 |
38035 |
| 手稿来源省、自治区或特别行政区 |
北京市 |
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Received |
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2020-11-25 00:54 |
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Peer-Review Started |
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2020-11-25 10:50 |
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To Make the First Decision |
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Return for Revision |
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2020-12-21 02:36 |
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修回稿 |
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2020-12-24 06:26 |
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Second Decision |
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2021-01-15 09:23 |
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期刊总编辑接受 |
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公司总编辑接受 |
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2021-01-18 01:30 |
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预出版 |
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2021-01-18 01:30 |
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缴纳版面费 |
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Edit the Manuscript by Language Editor |
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排版 |
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2021-02-28 02:17 |
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在线出版 |
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2021-03-01 11:10 |
| ISSN |
1009-3079 (print) and 2219-2859 (online) |
| 开放获取 |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| 版权 |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| 网址 |
http://www.wjgnet.com |
| 专业类型 |
消化基础研究 |
| 手稿栏目类型 |
文献综述 |
| 文章标题 |
肠道M细胞的功能与疾病的研究进展
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| 手稿来源 |
自由来稿 |
| 所有作者列表 |
李秋璇, 郭玥盺, 华嵘暄, 尚宏伟, 李利生, 徐敬东 |
| ORCID |
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| 基金项目及其编号 |
| 基金项目名称 |
基金编号 |
| 国家自然科学基金资助项目 |
81274173, 81673671 |
| 国家重点研发计划“重大慢性非传染性疾病防控研究”重点专项课题 |
2016YFC1306305 |
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| 通讯作者 |
徐敬东, 博士, 副教授, 100069, 北京市丰台区右安门外西头条10号, 首都医科大学生理学与病理生理学系. xujingdong@163.com |
| 关键词 |
M细胞; 信号通路; 肠道免疫; 分化; 克罗恩病; 肺结核 |
| 核心内容提要 |
M细胞来源于肠隐窝Lgr5+干细胞, 成熟的M细胞基底膜向上突起, 呈“囊袋状”, 该结构提高了M细胞摄取转运抗原的效率. M细胞可引发免疫应答, 却又是病原体侵袭人体的靶点, 其分化过程中RANKL和S100A4蛋白至关重要. |
| 出版日期 |
2021-03-01 11:10 |
| 引文著录 |
李秋璇, 郭玥盺, 华嵘暄, 尚宏伟, 李利生, 徐敬东. 肠道M细胞的功能与疾病的研究进展. 世界华人消化杂志 2021; 29(4): 197-203 |
| URL |
https://www.wjgnet.com/1009-3079/full/v29/i4/197.htm |
| DOI |
https://dx.doi.org/10.11569/wcjd.v29.i4.197 |
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