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2021/11/28 13:14:57 | Browse: 358 | 下载: 380
| Publication Name |
世界华人消化杂志 |
| 手稿编号 |
38468 |
| 手稿来源省、自治区或特别行政区 |
浙江省 |
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Received |
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2021-07-09 10:46 |
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Peer-Review Started |
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2021-07-10 02:25 |
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To Make the First Decision |
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Return for Revision |
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2021-08-23 17:01 |
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修回稿 |
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2021-08-25 12:52 |
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Second Decision |
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2021-10-14 11:11 |
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期刊总编辑接受 |
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公司总编辑接受 |
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2021-10-15 05:34 |
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预出版 |
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2021-10-15 05:34 |
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缴纳版面费 |
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Edit the Manuscript by Language Editor |
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排版 |
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2021-11-27 15:13 |
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在线出版 |
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2021-11-28 13:14 |
| ISSN |
1009-3079 (print) and 2219-2859 (online) |
| 开放获取 |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| 版权 |
©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| 网址 |
http://www.wjgnet.com |
| 专业类型 |
消化基础研究 |
| 手稿栏目类型 |
基础研究 |
| 文章标题 |
circ_0000212靶向miR-139-5p对肝癌细胞增殖、迁移、侵袭、凋亡以及紫杉醇敏感性的影响
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| 手稿来源 |
自由来稿 |
| 所有作者列表 |
张惠忠, 张晓东, 黄建新 |
| ORCID |
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| 基金项目及其编号 |
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| 通讯作者 |
张惠忠, 本科, 主治医师, 321111, 浙江金华环城北路1296号, 金华广福肿瘤医院肝胆胰胃外科. drzhanghuizhong@163.com |
| 关键词 |
circ_0000212; miR-139-5p; 肝癌; 细胞增殖; 凋亡; 迁移; 侵袭; 紫杉醇敏感性 |
| 核心内容提要 |
肝癌组织中circ_0000212表达上调, miR-139-5p表达下调. circ_0000212可靶向负调控miR-139-5p表达. 干扰circ_0000212通过靶向上调miR-139-5p可抑制肝癌细胞增殖、迁移、侵袭能力, 诱导细胞凋亡, 并提高其对紫杉醇的敏感性. circ_0000212和miR-139-5p可能是紫杉醇化疗增敏、抑制肝癌进展的潜在靶点. |
| 出版日期 |
2021-11-28 13:14 |
| 引文著录 |
张惠忠, 张晓东, 黄建新. circ_0000212靶向miR-139-5p对肝癌细胞增殖、迁移、侵袭、凋亡以及紫杉醇敏感性的影响. 世界华人消化杂志 2021; 29(22): 1276-1285 |
| URL |
https://www.wjgnet.com/1009-3079/full/v29/i22/1276.htm |
| DOI |
https://dx.doi.org/10.11569/wcjd.v29.i22.1276 |
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