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2023/6/8 14:00:42 | Browse: 310 | 下载: 342
| Publication Name |
世界华人消化杂志 |
| 手稿编号 |
39457 |
| 手稿来源省、自治区或特别行政区 |
湖南省 |
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Received |
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2023-04-18 01:59 |
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Peer-Review Started |
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2023-04-18 02:20 |
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To Make the First Decision |
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Return for Revision |
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2023-04-28 16:42 |
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修回稿 |
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2023-05-04 15:00 |
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Second Decision |
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2023-05-18 12:21 |
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期刊总编辑接受 |
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公司总编辑接受 |
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2023-05-18 21:34 |
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预出版 |
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2023-05-18 21:34 |
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缴纳版面费 |
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Edit the Manuscript by Language Editor |
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排版 |
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2023-06-08 10:18 |
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在线出版 |
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2023-06-08 14:00 |
| ISSN |
1009-3079 (print) and 2219-2859 (online) |
| 开放获取 |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| 版权 |
© The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| 网址 |
http://www.wjgnet.com |
| 专业类型 |
消化内科学 |
| 手稿栏目类型 |
基础研究 |
| 文章标题 |
附子理中丸治疗肠结核作用机制的网络药理学研究
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| 手稿来源 |
自由来稿 |
| 所有作者列表 |
苏敏, 钱纯, 张贞, 姜思宇, 李菁, 李云豪, 周辉 |
| 基金项目及其编号 |
| 基金项目名称 |
基金编号 |
| 湖南省教育厅：优秀青年项目《基于串联可变重复序列的结核分枝杆菌及其耐药特性的快速检测方法研究 》 |
20B435 |
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| 通讯作者 |
周辉, 博士, 教授, 主任检验师, 410000, 湖南省长沙市雨花区韶山中路95号, 湖南中医药大学第一附属医院医学检验中心. zyfyjianyan@163.com |
| 关键词 |
肠结核; 附子理中丸; 网络药理学; 细胞因子 |
| 核心内容提要 |
本研究基于网络药理学分析, 构建了附子理中丸与肠结核蛋白互作网络, 并筛选出附子理中丸作用于肠结核的10个核心靶点, 通过京都基因和基因组百科全书富集分析和基因本体论分析发现了治疗作用机制与氧化应激、细胞因子参与的炎症或免疫调节相关. |
| 出版日期 |
2023-06-08 14:00 |
| 引文著录 |
苏敏, 钱纯, 张贞, 姜思宇, 李菁, 李云豪, 周辉. 附子理中丸治疗肠结核作用机制的网络药理学研究. 世界华人消化杂志 2023; 31(11): 446-455 |
| URL |
https://www.wjgnet.com/1009-3079/full/v31/i11/446.htm |
| DOI |
https://dx.doi.org/10.11569/wcjd.v31.i11.446 |
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