Publication Name	世界华人消化杂志
手稿编号	40397
手稿来源省、自治区或特别行政区	新疆维吾尔自治区

Received	2025-09-29 01:10
Peer-Review Started	2025-09-29 07:14
To Make the First Decision
Return for Revision	2025-10-31 04:04
修回稿	2025-11-08 11:16
Second Decision	2026-01-21 03:52
期刊总编辑接受
公司总编辑接受	2026-01-21 08:22
预出版	2026-01-21 08:22
缴纳版面费
Edit the Manuscript by Language Editor
排版	2026-01-28 08:34
在线出版	2026-01-28 13:21

ISSN	1009-3079 (print) and 2219-2859 (online)
开放获取	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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专业类型	消化肿瘤学
手稿栏目类型	基础研究
文章标题	MicroRNA-21表达调节对人胃癌细胞MKN-45对奥沙利铂耐药性的影响
手稿来源	自由来稿
所有作者列表	金博, 刘林, 刘玉婷
ORCID	作者 ORCID Number 金博 http://orcid.org/0000-0002-4653-3406 刘林 http://orcid.org/0009-0009-9144-1859
基金项目及其编号
通讯作者	刘林, 博士, 副教授, 主任医师, 831001, 新疆乌鲁木齐新市区苏州东街789号, 新疆医科大学附属肿瘤医院胃肠外科一病区. 13899843593@163.com
关键词	胃癌; MicroRNA-21; 耐药性; 奥沙利铂; P糖蛋白
核心内容提要	MicroRNA-21(miR-21)可能在胃癌细胞对化疗药物耐药过程中发挥作用. 本研究显示, 下调其表达可在一定程度上逆转对奥沙利铂耐药的MKN-45的耐药性, miR-21可能成为胃癌治疗的新靶点.
出版日期	2026-01-28 13:21
引文著录	金博, 刘林, 刘玉婷. MicroRNA-21表达调节对人胃癌细胞MKN-45对奥沙利铂耐药性的影响. 世界华人消化杂志 2026; 34(1): 78-84
URL	https://www.wjgnet.com/1009-3079/full/v34/i1/78.htm
DOI	https://dx.doi.org/10.11569/wcjd.v34.i1.78

Full Article (PDF)	WCJD-34-78-with-cover.pdf
审稿意见	WCJD-40397-Peer-review(s).pdf
科学编辑工作清单	WCJD-40397-Scientific editor work list.pdf