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2026/9/2 9:25:06 | Browse: 7 | 下载: 0
| Publication Name |
世界华人消化杂志 |
| 手稿编号 |
40563 |
| 手稿来源省、自治区或特别行政区 |
青海省 |
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Received |
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2026-05-21 05:45 |
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Peer-Review Started |
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2026-05-21 09:37 |
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To Make the First Decision |
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Return for Revision |
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2026-06-05 11:05 |
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修回稿 |
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2026-06-18 09:08 |
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Second Decision |
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2026-06-29 07:25 |
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期刊总编辑接受 |
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公司总编辑接受 |
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2026-07-01 11:24 |
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预出版 |
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2026-07-01 11:24 |
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缴纳版面费 |
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Edit the Manuscript by Language Editor |
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排版 |
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2026-08-27 08:14 |
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在线出版 |
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2026-09-02 09:25 |
| ISSN |
1009-3079 (print) and 2219-2859 (online) |
| 开放获取 |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| 版权 |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| 网址 |
http://www.wjgnet.com |
| 专业类型 |
消化肿瘤学 |
| 手稿栏目类型 |
文献综述 |
| 文章标题 |
胃癌表观遗传学发生机制及耐药的研究进展
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| 手稿来源 |
约稿 |
| 所有作者列表 |
祁玉娟, 蹇卓雅 |
| 基金项目及其编号 |
| 基金项目名称 |
基金编号 |
| 青海省科技厅自然科学基金课题(面上项目) |
2023-ZJ-938M |
| 青海省“昆仑英才·高端创新创业人才”培养杰出人才项目 |
青人才字[2025]12号 |
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| 通讯作者 |
祁玉娟, 博士, 教授, 主任医师, 810007, 青海省人民医院青海省西宁市城东区共和路2号, 青海省人民医院肿瘤内科. qiyujuan1108@126.com |
| 关键词 |
胃癌; 表观遗传学; 耐药; 肿瘤 |
| 核心内容提要 |
胃癌是全球高发恶性肿瘤, 耐药与异质性制约临床疗效. 表观遗传不改变DNA序列, 通过非编码RNA、DNA甲基化、组蛋白修饰调控基因表达, 驱动胃癌发生、侵袭转移与化疗耐药. miRNA、lncRNA可作为诊断与预后标志物, DNA甲基化与组蛋白去乙酰化抑制剂单用或联用有望逆转耐药, 为胃癌精准诊疗与克服耐药提供全新方向. |
| 出版日期 |
2026-09-02 09:25 |
| 引文著录 |
祁玉娟, 蹇卓雅. 胃癌表观遗传学发生机制及耐药的研究进展. 世界华人消化杂志 2026; 34(8): 609-615 |
| URL |
https://www.wjgnet.com/1009-3079/full/v34/i8/609.htm |
| DOI |
https://dx.doi.org/10.11569/wcjd.v34.i8.609 |
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