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2018/11/8 11:03:51 | Browse: 731 | 下载: 653
Publication Name |
世界华人消化杂志 |
手稿编号 |
36306 |
手稿来源省、自治区或特别行政区 |
湖北省 |
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Received |
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2018-08-22 09:16 |
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Peer-Review Started |
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2018-08-22 09:57 |
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To Make the First Decision |
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2018-09-11 08:10 |
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Return for Revision |
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2018-09-12 01:49 |
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修回稿 |
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2018-09-29 01:48 |
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Second Decision |
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2018-10-18 08:12 |
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期刊总编辑接受 |
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公司总编辑接受 |
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2018-10-18 23:58 |
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预出版 |
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2018-10-18 23:58 |
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缴纳版面费 |
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Edit the Manuscript by Language Editor |
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排版 |
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2018-11-06 08:15 |
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在线出版 |
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2018-11-08 11:03 |
ISSN |
1009-3079 (print) and 2219-2859 (online) |
开放获取 |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
版权 |
© The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
网址 |
http://www.wjgnet.com |
专业类型 |
消化内科学 |
手稿栏目类型 |
基础研究 |
文章标题 |
非酒精性脂肪性肝病合并2型糖尿病大鼠模型的建立
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手稿来源 |
自由来稿 |
所有作者列表 |
柯淑红, 郑承红, 彭聪, 周扬, 马威 |
基金项目及其编号 |
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通讯作者 |
柯淑红, 研究生, 主治医师, 430022, 湖北省武汉市江岸区黎黄陂路49号, 武汉市中医院内分泌科. keshu1980@aliyun.com |
关键词 |
非酒精性脂肪性肝病; 链脲佐菌素; 高糖高脂饮食; 2型糖尿病 |
核心内容提要 |
非酒精性脂肪性肝病(non-alcoholic fatty liver disease, NAFLD)并非单一的肝脏疾病, 是胰岛素抵抗及2型糖尿病等代谢综合征相关组分在肝脏集中表现, 目前营养和药物复合诱导的NAFLD动物模型, 因能涵盖NAFLD疾病特征, 广泛应用于基础研究, 但仍普遍存在造模方法及判定模型成功标准不统一的问题, 以葡萄糖耐量试验及时间-血糖曲线下面积作为判定模型成功标准之一, 能模拟NAFLD代谢紊乱背景并尽可能减少诱导药物的不良影响. |
出版日期 |
2018-11-08 11:03 |
引文著录 |
柯淑红, 郑承红, 彭聪, 周扬, 马威. 非酒精性脂肪性肝病合并2型糖尿病大鼠模型的建立. 世界华人消化杂志 2018 |
URL |
http://www.wjgnet.com/1009-3079/full/v26/i31/1805.htm |
DOI |
http://dx.doi.org/10.11569/wcjd.v26.i31.1805 |
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